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Technical Information Magazine 202201-02 fsLA-ICP-MS

Technical Information Magazine 202201-02 fsLA-ICP-MS

Femtosecond laser ablation-inductively coupled plasma mass spectrometry is a useful method for analyzing the two-dimensional distribution of elements present in trace amounts in biological tissues.

The technical information magazine The TRC News provides the latest information on analytical techniques that are useful for research and development, solving production troubles, and quality control. [Abstract] fsLA-ICP-MS (femtosecond laser ablation-inductively coupled plasma mass spectrometry) is a method capable of rapidly and sensitively analyzing inorganic elements in solid samples at a local level, and it has garnered attention as a useful technique for two-dimensional distribution analysis of elements present in trace amounts within biological tissues. This paper introduces the characteristics of fsLA-ICP-MS, examples of drug distribution evaluation in tissues, and quantitative imaging examples using custom-prepared standards. [Table of Contents] 1. Introduction 2. Overview and Characteristics of fsLA-ICP-MS 3. Evaluation of Boron Drug Distribution for BNCT 4. Quantitative Imaging of Iron and Zinc in Mouse Spinal Cord 5. Conclusion

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Technical Information Magazine 202304-02 Optical-PTIR

Technical Information Magazine 202304-02 Optical-PTIR

This paper presents examples of measuring non-fixed cells under physiological conditions to visualize the distribution and localization of cellular components (such as proteins and nucleic acids).

The technical information magazine The TRC News provides the latest information on analytical techniques that are useful for research and development, solving production troubles, and quality control. **Abstract** Infrared spectroscopy is a method for obtaining information about molecular structure by measuring infrared absorption due to molecular vibrations. Utilizing photothermal conversion, O-PTIR (Optical Photothermal IR Spectroscopy) enables infrared analysis with sub-micron spatial resolution and non-contact measurement. This paper presents a case study of measuring non-fixed cells under physiological conditions to visualize the distribution and localization of cellular components (such as proteins and nucleic acids). **Table of Contents** 1. Introduction 2. Overview and Features of O-PTIR 3. Analysis of Suspended Living Cells (Budding Yeast) in Water - Comparison of Intracellular Spectra - 4. Analysis of Suspended Living Cells (Budding Yeast) in Water - Distribution of Cellular Components - 5. Conclusion

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Technical Information Magazine 201903-01 Cutting-edge SIMS Analysis Equipment

Technical Information Magazine 201903-01 Cutting-edge SIMS Analysis Equipment

The technical information magazine The TRC News provides the latest information on analytical techniques that are useful for research and development, solving production troubles, and quality control.

**Abstract** The state-of-the-art secondary ion mass spectrometry (SIMS) device, NanoSIMS 50L, enables imaging measurements with spatial resolution approximately two orders of magnitude higher than conventional SIMS, thanks to its ion beam with a probe diameter of about 50 nm and a highly efficient mass analysis system. This paper introduces the features of the NanoSIMS 50L device and analysis examples. **Table of Contents** 1. Introduction 2. Overview of the Analytical Device 3. Analysis Example of Hair Cross-Section 4. Analysis Example of SiC Semiconductor Devices 5. Conclusion

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Protein Metrics-hosted User Group Meeting

Protein Metrics-hosted User Group Meeting

I will give a presentation at the user group meeting hosted by Protein Metrics.

We will introduce the key factors for the introduction of Byos at the Toray Research Center and examples of its utilization. Date and Time: November 29 (Friday) starting at 1:00 PM (Doors open at 12:30 PM) Location: Breeze Plaza Address: 2-4-9 Umeda, Kita-ku, Osaka 530-0001, Breeze Tower

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Technical Information Magazine 202401-01 ICP Emission Spectroscopy Method

Technical Information Magazine 202401-01 ICP Emission Spectroscopy Method

When quantifying inorganic elements using ICP emission spectrometry, the validity of the solution preparation method is important. This article introduces points to consider when quantifying boron (B).

The technical information magazine The TRC News provides the latest information on analytical techniques that are useful for research and development, resolving production troubles, and quality control. [Abstract] The accuracy of analytical values when quantifying inorganic elements in various materials using ICP emission spectrometry depends on the validity of the dissolution method and its effectiveness. This paper introduces specific points to be particularly mindful of when quantifying boron (B). [Table of Contents] 1. Introduction 2. Chemical pretreatment for boron analysis 3. Conclusion

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